Shobhan Gaddameedhi

Associate Professor

Research Brief

Shobhan Gaddameedhi received his master’s degree in Plant Sciences from the University of Hyderabad, India and PhD in Pharmaceutical Sciences from North Dakota State University. He pursued his post-doctoral training in the circadian biology and DNA repair fields with Prof. Aziz Sancar, at the University of North Carolina Chapel Hill. Before joining as an Associate Professor at NC State in July 2020, he worked as an Assistant Professor at Washington State University (2014-2020). His laboratory is currently focused on three major areas of investigation on human health: (1) unraveling the molecular basis for circadian clock and DNA damage repair roles in environmental health outcomes through ‘gene-environment’ interactions; (2) understanding the mechanistic basis for genomic instability and environmental carcinogenesis through circadian disruption by shift work; and (3) understanding the effect of emerging environmental contaminants on circadian rhythmicity, sleep and DNA damage response signaling. Currently his laboratory is funded by the NIH, DOD/CDMRP, Melanoma Research Alliance (MRA) and NC State startup grants. He has authored 28 peer-reviewed publications including PNAS (3), Cancer Research (2), JBC (2), Genes & Development (1) and 2 invited book chapters.