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NC State University and the Research Triangle Park

NC State University is a premier research university committed to excellence in teaching, research, and service to the larger community. NC State University is located in Raleigh, North Carolina, just 15 miles from the Research Triangle Park, one of the most prominent telecommunications, environmental health, pharmaceutical and biotechnology research centers in the United States. Recognized internationally as a center for cutting-edge research and development, the 7,000-acre Research Triangle Park is the largest research park in the United States, and is home to over 140 private and government organizations with 42,000 full-time employees. The Research Triangle itself is named for the Triangle formed by the three cities in which major research universities are located: Duke University of Durham, the University of North Carolina at Chapel Hill, and NC State University in Raleigh.
Toxicology Building on Centennial Campus

Toxicology Building

Toxicology moved into a state-of-the-art, 59,000 square foot building in April 2001 that brought faculty, Department, staff, and students together under one roof and with excellent facilities for teaching and research. The Toxicology Building is located on NC State University’s Centennial Campus in Raleigh, North Carolina, a 3,000 acre advanced technology community for university, industry and government partners.

Research Facilities

The laboratory wing of the Toxicology Building houses modern and flexible laboratories for molecular, cellular, and environmental toxicology research. Laboratories for individual faculty are augmented by multipurpose, special-purpose, and common-equipment rooms.

These include:

  • Small animal facility
  • Aquatic toxicology lab with proportional diluter systems for flow-through experiments and tanks for organism culture and static experiments
  • Shared equipment rooms with scintillation counters, autoclaves, gas and liquid chromatographs, mass spectrometers, mercury analyzer, gel and capillary electrophoresis, ultracentrifuges, high speed and table-top centrifuges, shaker incubators, freezers and refrigerators, autoclaves, UV-crosslinkers, gel dryers, PCR and RT-PCR
  • High hazard laboratory with special accommodations for working with highly toxic chemicals
  • Cell culture rooms
  • Dark rooms with film processors, UVP transilluminators, and camera sets
  • Faculty, student and technical staff offices

The NCSU Genome Research Laboratory, a resource for all NCSU faculty engaged in genomic research, is located in Thomas Hall on Main Campus. The equipment is readily accessible and available at no charge to Toxicology faculty, students, and staff:

  • 3 Perkin Elmer Prism 3700 96-capillary Automated DNA Sequencers. 6,250 sequences can be run in a 5-day week.
  • Genetix Qarray 10,000 spots per field, 2 fields per slide, and 210 slides per batch in = 3 hours.
  • General Scanning ScanArray 4000 Microarrayer Scanner. Interchangeable lasers for different dye chemistries.
  • 2 Qiagen BioBot 9600 Liquid handling robots. 96-well plasmid prep in 1 hour. 96-well sequencing reaction set-up in 1 hour.
  • 1 Perkin Elmer 1000 thermocycler for in situ reactions and microarray hybridizations.
  • 1 Genetix Qbot. Picks 3,500 colonies/hour, plate consolidation, filter spotting: 15 filters with 36,864 clones/filter in < 3 hours.

Additional research facilities available at NC State include:

  • The Center for Electron Microscopy
  • Monoclonal Antibody Facility
  • Nucleic Acid Facility
  • DNA Sequencing Facility
  • Mass Spectrometry Facility
  • Nuclear Magnetic Resonance Facility
  • Cell and Molecular Imaging Facility
  • Several Analytical Service Facilities
  • Center for Cutaneous Toxicology and Residue Pharmacology
  • Bioinformatics Research Center
  • Center for Marine Science and Technology.

For a full list (with links) of NCSU biotechnology research facilities, visit: http://www.ncsu.edu/biotechnology/?p=facilities&sub=at_ncsu.

Other research facilities are available in the laboratories of adjunct faculty and collaborators at nearby institutions in Research Triangle Park, including NIEHS, EPA, The Hamner Institutes for Health Sciences (CIIT), GSK, UNC Chapel Hill and Duke University. The aggregate resources of NC State and these other institutions have made the Research Triangle Park the world’s center for toxicology research.

Teaching Facilities

In addition to our excellent research laboratories, students enjoy the use of our computer laboratory with 20 workstations, a library with journals, books, and a quiet and comfortable place to study, and a 120-seat auditorium where we hold our classes and host numerous workshops and local/regional conferences.