Jun Ninomiya-Tsuji
JN
Education
Postdoc DNAX Research Institute, CA
Postdoc Affymax Research Institute, CA
PhD Hiroshima University, Japan
Publications
- TAK1 inhibition activates pore-forming proteins to block intracellular bacterial growth through modulating mitochondria , Cell Death and Disease (2025)
- Abstract 1191 TAK1 inhibition translocates pore-forming proteins, MLKL and gasdermins into mitochondria to generate reactive oxygen species , Journal of Biological Chemistry (2024)
- Abstract 1192 The Mechanism and Roles of TAK1 hyperactivation in the Alzheimer's Disease Mouse Model , Journal of Biological Chemistry (2024)
- Modulation of iron metabolism by new chemicals interacting with the iron regulatory system , Redox Biology (2024)
- Aberrantly activated TAK1 links neuroinflammation and neuronal loss in Alzheimer's disease mouse models , Journal of Cell Science (2023)
- TAK1 inhibition elicits mitochondrial ROS to block intracellular bacterial colonization , Proceedings of the National Academy of Sciences (2021)
- Coordinating Tissue Regeneration Through Transforming Growth Factor-β Activated Kinase 1 Inactivation and Reactivation , Stem Cells (2019)
- Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing , The Journal of Cell Biology (2019)
- Compound mutations in Bmpr1a and Tak1 synergize facial deformities via increased cell death , genesis (2018)
- Erratum: Noncanonical cell death program independent of caspase activation cascade and necroptotic modules is elicited by loss of TGFβ-activated kinase 1 , Scientific Reports (2017)